Drug combination therapy for emerging viral diseases

Emerging zoonotic viral diseases.

Zoonotic diseases are infectious diseases that are naturally transmitted from vertebrate animals to humans and vice versa. They are caused by all types of pathogenic agents, including bacteria, parasites, fungi, viruses and prions. Although they have been recognised for many centuries, their impact on public health has increased in the last few decades due to a combination of the success in red...

Emerging viral diseases.

Prevention of viral drug resistance by novel combination therapy.

A new form of antiviral clinical therapy is proposed in which three different drugs are administered against three different targets on the same virus-coded protein. If the physiological functions of the three different target sites are not independent of each other, then a mutation conferring drug resistance at one site may alter the physiological functions at the other sites and further drug ...

The importance of vaccination in the control of the emerging viral diseases outbreaks

During the past decade several new viruses have emerged  making a  global health threat. The most pandemic threats are due to the  either zoonotic or  vector-borne viruses. The emerging of new infectious diseases continue to  be threaten of public health and the social activities including traveling or trade help to sustain and spread of the viruses.  Developing methods to manage and predict th...

Emerging Drug Therapies for Heart Failure

Heart failure is associated with high morbidity and mortality and is proving to be an economic burden in developing countries. A number of therapeutic agents are presently employed in heart failure; but they are not sufficient to control symptoms of heart failure. Moreover, the prevalence of chronic heart failure is progressively increasing and thus there is a continuing need to develop effecti...